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Human immunodeficiency virus 1 (HIV-1) encodes a gene product, Vpr, that facilitates the nuclear uptake of the viral pre-integration complex in non-dividing cells and causes infected cells to arrest in the G(2) phase of the cell cycle. Vpr was also shown to cause mitochondrial dysfunction in human cells and budding yeasts, an effect that was proposed to(More)
Verification and validation (V&amp;V) techniques are used in agent-based modeling (ABM) to determine whether the model is an accurate representation of the real system. Docking is a form of V&V that tries to align multiple simulation models. In a previous paper, we described the docking process of an ABM that simulates the life cycle of <i>Anopheles(More)
Field-coupled nanomagnets can offer significant energy savings at iso-performance versus CMOS equivalents. Magnetic logic could be integrated with CMOS, operate in environments that CMOS cannot, and retain state without power. Clocking requirements lead to inherently pipelined circuits, and high throughput further improves application-level performance.(More)
In the practise of veterinary medicine and global public health, communication skill is as critical as clinical reasoning and an extensive knowledge base. Effective communication skills and cross-cultural sensitivity are essential across the board for interdisciplinary, international, and local veterinary medicine. This paper offers an evidence-based,(More)
This paper presents a rationale for including the construction of interactive simulations in an Information Technology (IT) curriculum, describes ongoing work in the Shared Extensible Learning Spaces (SHELS) project, and describes how we integrate that work into our curriculum. As computing technologies advance, the complexity of the data generated(More)
This presentation explores the power of simulation building as a constructivist learning activity and develops an agenda for the pursuit of research in this area. Our project evolved out of repeated observations that multimedia students, working as programmers and designers on agent-based computer simulations of complex adaptive systems, often became(More)
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