Steve Gerges

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Treatment resistance in acute lymphoblastic leukemia (ALL) is often caused by defects in programmed cell death, e.g. by overexpression of Inhibitor of Apoptosis (IAP) proteins. Here, we report that small-molecule Smac mimetics (i.e. BV6, LCL161, birinapant) that neutralize x-linked IAP (XIAP), cellular IAP (cIAP)1 and cIAP2 cooperate with demethylating(More)
Motion features based on optical flow are very powerful in tasks such as the recognition of human actions or gestures. Usually, they are combined with gradient information to form a set of spatiotemporal features. However, humans can recognize gestures and actions and thus derive the implied motion out of static images alone. We model this associative(More)
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