Steve Cohen

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Most malaria drug development focuses on parasite stages detected in red blood cells, even though, to achieve eradication, next-generation drugs active against both erythrocytic and exo-erythrocytic forms would be preferable. We applied a multifactorial approach to a set of >4000 commercially available compounds with previously demonstrated blood-stage(More)
Ethanol extracts of Myxococcus xanthus contained several substances, referred to as autocides, which were bactericidal to the producing strain but showed no activity against other bacteria. The autocides were produced by growing cells and remained largely cell bound throughout the growth cycle; ca. 5% of the autocidal activity was found in the supernatant(More)
PURPOSE To determine the safety and efficacy of preoperative hypofractionated radiotherapy using intensity-modulated radiotherapy (IMRT) and an incorporated boost with concurrent capecitabine in patients with locally advanced rectal cancer. METHODS AND MATERIALS The eligibility criteria included adenocarcinoma of the rectum, T3-T4 and/or N1-N2 disease,(More)
Purpose While mathematics education guidelines have encouraged substantial change in the introductory probability and statistics curriculum, probability distributions still remain an important topic in a first course. In fact, just as software has made data analysis more accessible to students in introductory courses, it also offers new ways to teach(More)
The Bureau of Labor Statistics (BLS) Quarterly Census of Employment and Wages (QCEW) is a census that collects data under a cooperative program between BLS and the State Employment Security Agencies. The data contain broad employment and wage information for all U.S. workers covered by state unemployment insurance laws and federal workers covered by the(More)
BACKGROUND It is well known that obesity is accompanied by changes in thyroid function. Hypothyroidism is associated with increased body weight. The aim of this study was to evaluate the operative outcomes, weight loss, and the effect of weight loss on thyroid function in morbidly obese patients with hypothyroidism who undergo laparoscopic Roux-en-Y gastric(More)