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Functional magnetic resonance imaging (fMRI) provides a safe, noninvasive method for studying task-related cortical neuronal activity. Because the cerebral cortex is strongly implicated in the control of human swallowing, we sought to identify its functional neuroanatomy using fMRI. In 10 healthy volunteers, a swallow event-related paradigm was performed by(More)
This investigation used a derivation of acoustic reflection (AR) technology to make cross-sectional measurements of changes due to aging in the oral and pharyngeal lumina of male and female speakers. The purpose of the study was to establish preliminary normative data for such changes and to obtain acoustic measurements of changes due to aging in the(More)
Research examining physiologic and acoustic characteristics of culturally diverse populations is sorely needed, but rarely reported. The major aim of this study was to quantify vocal tract dimensional parameters (oral length, oral volume, pharyngeal length, pharyngeal volume, total vocal tract length and total vocal tract volume) of adult male speakers from(More)
The presence and transcriptional expression of Epstein-Barr virus (EBV)-encoded genes, oestrogen receptor (ER) status and degree of lymphocyte infiltration were evaluated in 15 mastectomy-removed breast cancer samples, mostly of ductal origin. With regard to these parameters, the tumours were heterogeneous. Viral genes, including EBNA1 - a universal EBV(More)
PURPOSE To compare the vocal tract configuration between male speakers with Class III malocclusion and their normally developing counterparts and to investigate the concomitant acoustic changes caused by the alterations in vocal tract configuration. PATIENTS AND METHODS Eight young male patients with Class III malocclusion and 8 normally developing(More)
Transcranial magnetic stimulation (TMS) over human fronto-central areas of scalp can activate short latency responses in the muscles of the face, pharynx and oesophagus. However, the physiological relationship between this early activity and the swallowing activity programmed by the brainstem central pattern generator (CPG) remains unclear. The aim of this(More)
BACKGROUND The influence of different types and intensities of physical activity on risk for breast cancer is unclear. METHODS In a prospective cohort of 73,049 Chinese women (40-70 years), who had worked outside the home, we studied breast cancer risk in relation to specific types of self-reported and work history-related physical activity, including(More)
This study sought to provide preliminary normative data for the vocal productions of 44 Euro-American and 40 African-American elderly speakers and to test the hypotheses that (1) Euro-American elderly speakers do not have significantly different acoustic parameters of voice from African-American elderly speakers, and (2) elderly male speakers (both(More)
There are no objective differences in neural elements that explain regional differences in neural influences along the smooth muscle (SM) esophageal body (EB). Regional differences in muscle properties are present in the lower esophageal sphincter (LES). This study examines whether regional differences in SM properties exist along the EB and are reflected(More)