Sterling Field

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In this study, we have used the tumor promoter 12-o-tetradecanoylphorbol-13-acetate (TPA), as well as its biologically inactive analogue 4 alpha-phorbol 12,13-didecanoate (4 alpha-PDD), to investigate platelet protein phosphorylation and its possible correlation with platelet activation. Our data show that TPA, but not 4 alpha-PDD, induces a preferential(More)
In mammals, left-right symmetry is broken during development by motile cilia-driven fluid flow in the embryonic node. How this 'nodal flow' is sensed remains the subject of debate. In kidney, fluid flow/membrane stress is sensed by polycystin protein complexes composed of Pkd1 and Pkd2 which reside in primary cilia. Pkd2 also plays a role in determining(More)
Sexual reproduction in plants requires development of haploid gametophytes from somatic tissues. Pollen is the male gametophyte and develops within the stamen; defects in the somatic tissues of the stamen and in the male gametophyte itself can result in male sterility. The maize fuzzy tassel (fzt) mutant has a mutation in dicer-like1 (dcl1), which encodes a(More)
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