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Chlamydia trachomatis Tarp harbors distinct G and F actin binding domains that bundle actin filaments.
- Shahanawaz Jiwani, Stephenie Alvarado, R. J. Ohr, A. Romero, B. Nguyen, T. Jewett
- Biology, Medicine
- Journal of bacteriology
- 15 February 2013
All species of Chlamydia undergo a unique developmental cycle that transitions between extracellular and intracellular environments and requires the capacity to invade new cells for dissemination. A… Expand
The Bis(Indolyl)Imidazole Alkaloid Nortopsentin A Exhibits Antiplasmodial Activity
- Stephenie Alvarado, Bracken F Roberts, A. Wright, D. Chakrabarti
- Biology, Medicine
- Antimicrobial Agents and Chemotherapy
- 12 February 2013
ABSTRACT A library of enriched marine natural product fractions was screened for their antiplasmodial activity using a SYBR green I fluorescence-based assay. Fractions derived from a sponge of the… Expand
Chlamydia trachomatis Tarp cooperates with the Arp2/3 complex to increase the rate of actin polymerization.
- Shahanawaz Jiwani, R. J. Ohr, +4 authors T. Jewett
- Biology, Medicine
- Biochemical and biophysical research…
- 20 April 2012
Actin polymerization is required for Chlamydia trachomatis entry into nonphagocytic host cells. Host and chlamydial actin nucleators are essential for internalization of chlamydiae by eukaryotic… Expand