Stephen Whipple

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Event-related potentials were recorded during a visual, continuous performance task from 36 boys before use of alcohol or other drugs began. The boys were sons of 13 recovering alcoholics who themselves had a family history of alcoholism, 11 nonalcoholics with a family history of alcoholism, and 12 nonalcoholics with no family history of alcoholism. Four(More)
Prepubescent boys and their recovering alcoholic fathers exhibited an Atypical Neurocognitive Profile consisting of (1) a reduction in amplitude of the late positive complex (LPC) of the event-related potential (ERP) during a complex visual discrimination task, and (2) reduced visuoperceptual performance evidenced by significantly lower scores on the Object(More)
This study examines the sensitivity of the University of Southern California Repeatable Episodic Memory Test (USC-REMT) to the effects of aging in a sample of 112 men and women from 18 to 93 years old. Two new recognition measures, yes-no and forced-choice, were developed to supplement the original USC-REMT which measured only free-recall. Free-recall,(More)
The University of Southern California Repeatable Episodic Memory Test (USC-REMT) was developed to provide a brief assay of memory in clinical drug trials where the same subject is tested multiple times over days or weeks. Therefore, it had to be minimally affected by repeated testing. The test also provides a measure of subjective organization, a cognitive(More)
ERPs were recorded during a simple color discrimination and a more difficult visual continuous performance task (CPT) from three father-son (n = 15) pair groups: recovering alcoholics with a family history of alcoholism and their sons (A+), nonalcoholics with a family history of alcoholism and their sons (NA+), and nonalcoholics with no family history of(More)
EEGs from Fz, Cz and Pz locations (reference--right mastoid) were obtained from 36 adults. For experimental trials the Fz slow potentials (SP) were determined for a pretask interval of: a 3 sec baseline, followed by a 2.5 sec SP shift, in either negative (3.5 microV) or positive (1.5 microV) direction, and maintenance at this level for another 2.5 sec. When(More)
Recovering alcoholic fathers with a positive family history of alcoholism and their 10-15 year-old sons were assessed on a variety of personality measures and compared to a matched group of nonalcoholic fathers with a negative family history of alcoholism, and their sons. Assessment instruments for the sons included the Personality Inventory for Children,(More)
Adult subjects were tested on a choice reaction time (RT) task for decisions of word pairs as synonyms or unrelated. For each trial the word stimuli were presented contingent upon computer-detection of a predetermined negative or positive EEG baseline shift, recorded from either parietal or frontal midline electrodes. With parietal slow potential (SP)(More)