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Transducer design and phased array beam steering are developed for a volumetric ultrasound scanner that enables the 3-D visualization of dynamic structures in real time. The authors describe the design considerations and preliminary evaluation of a high-speed, online volumetric ultrasound imaging system that uses the principles of pulse-echo, phased array(More)
OBJECTIVE To characterize the safety profile of tenofovir disoproxil fumarate (DF) for the treatment of HIV infection in adults over the first 4 years of use. METHODS A tenofovir DF expanded access program (EAP) was initiated in 2001; safety data were examined from this program and from the manufacturer's database, which contained reports of all(More)
The mechanism of death in patients struggling against restraints remains a topic of debate. This article presents a series of five patients with restraint-associated cardiac arrest and profound metabolic acidosis. The lowest recorded pH was 6.25; this patient and three others died despite aggressive resuscitation. The survivor's pH was 6.46; this patient(More)
For diagnostic ultrasound imaging, as in computed tomography, a feature of prime importance is the detection of focal lesions of varying size and contrast (echo amplitude) from surrounding tissue. This study describes a new tissue-stimulating phantom which has been used to measure the threshold detection of varying contrast, simulated lesions. The phantom(More)
Feasibility studies of autonomous robot biopsies in tissue have been conducted using real-time three-dimensional (3-D) ultrasound combined with simple thresholding algorithms. The robot first autonomously processed 3-D image volumes received from the ultrasound scanner to locate a metal rod target embedded in turkey breast tissue simulating a calcification,(More)
The National Opinion Research Center, led by a team of investigators at the University of Chicago, conducted more than 3,000 in-person interviews with a nationally representative sample of adults aged 57-85 years. Data collection included in-person questionnaire items, an extensive array of biomeasures, and a postinterview self-administered questionnaire.(More)
BACKGROUND We determined the diagnostic accuracy of the Advia Centaur TnI-Ultra assay for detecting myocardial infarction (MI) and assessing risk of adverse events in patients presenting with ischemic symptoms suggestive of acute coronary syndrome. METHODS We measured cardiac troponin I (cTnI) on admission and 6-24 h after admission (follow-up) in plasma(More)
A real time volumetric ultrasound imaging system has been developed for medical diagnosis. The scanner produces images analogous to an optical camera and supplies more information than conventional sonograms. Potential medical applications include improved anatomic visualization, tumor localization, and better assessment of cardiac function. The system uses(More)
BACKGROUND We sought to determine the diagnostic accuracy of the cardiac troponin I (cTnI) VITROS(R) Troponin I-ES assay for early detection of acute myocardial infarction (AMI) and for risk prediction of adverse events in patients with symptoms of acute coronary syndrome (ACS). METHODS cTnI was measured on admission and approximately 6 h postadmission in(More)