Stephen W. Looney

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PROBLEM Little is known about the effectiveness of a comprehensive psychoeducational intervention on depression, self-esteem, and parenting attitudes/beliefs of at-risk pregnant and parenting adolescents. METHODS Adolescents (N = 41) attending either a residential treatment facility (RTF) or a rural alternative school (RAS) participated in a(More)
Current research and theoretical frameworks for understanding motor dominance assume that motor dominance is primary. Various developmental clues, however, suggest that the maturation of proprioceptive sensory processing predates that of motor control. We hypothesized that the observed adult pattern of lateralized motor dominance may develop as a(More)
BACKGROUND Semaphorin 3A is a secreted protein that regulates cell motility and attachment in axon guidance, vascular growth, immune cell regulation and tumor progression. However, nothing is known about its role in kidney pathophysiology. Here, we determined whether semaphorin3A is induced after acute kidney injury (AKI) and whether urinary semaphorin 3A(More)
Up to 50% of oral squamous cell carcinomas (OSCCs) recur following surgical resections with conventional "histologically-negative" margins. Three members of the SIBLING family of proteins: dentin sialophophoprotein (DSPP); bone sialoprotein (BSP); and osteopontin OPN are upregulated in OSCCs. In this study, we aimed to correlate the expression of DSPP, OPN(More)
PURPOSE/OBJECTIVES to describe the quality of life (QOL) of patients near the end of life and to identify determinants of their QOL. DESIGN descriptive, longitudinal. SETTING university-affiliated cancer center, two private oncologists' offices, and patients' homes. SAMPLE 80 patients with either stage IIIb or IV lung cancer newly diagnosed in the(More)
One focus of interventions being developed for depression in nursing homes is increasing pleasant events. The conceptual foundation of such interventions requires establishing links among activity levels, depressive symptoms and positive affect. We observed activity and affect among 28 nursing home residents, five-days-a-week for four weeks, and(More)
BACKGROUND We determined recently that dentin sialophosphoprotein (DSPP), a member of the SIBLING (Small integrin-binding ligand N-linked glycoproteins) family of phosphoglycoproteins, is highly upregulated in human oral squamous cell carcinomas (OSCCs) where upregulation is associated with tumor aggressiveness. To investigate the effects of DSPP-silencing(More)
The problems associated with intra- and interexaminer reliability when assessing preclinical performance continue to hinder dental educators' ability to provide accurate and meaningful feedback to students. Many studies have been conducted to evaluate the validity of utilizing various technologies to assist educators in achieving that goal. The purpose of(More)
Tardive dyskinesia (TD) is a side effect of prolonged neuroleptic treatment presenting as abnormal involuntary movements. This troublesome disorder occurs in only 15-30% of patients taking neuroleptics, suggesting that these individuals may be physiologically distinct so as to be predisposed. This study analyzed possible factors contributing to TD(More)