Stephen S. Stahl

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Antibodies to the capsid (cAg, core antigen) of HBV play a central role in the immune response to this virus. Since most anti-cAg antibodies recognize conformational epitopes, ruling out characterization by immunochemical methods, we have approached the problem by cryo-EM and image reconstruction of Fab-decorated capsids, combined with molecular modelling.(More)
We describe a novel interaction between HIV-1 Rev and microtubules (MTs) that results in the formation of bilayered rings that are 44-49 nm in external diameter, 3.4-4.2 MD (megadaltons) in mass, and have 28-, 30-, or 32-fold symmetry. Ring formation is not sensitive to taxol, colchicine, or microtubule-associated proteins, but requires Mg(2+) and is(More)
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