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The extraction of the centerlines of tubular objects in two and three-dimensional images is a part of many clinical image analysis tasks. One common approach to tubular object centerline extraction is based on intensity ridge traversal. In this paper, we evaluate the effects of initialization, noise, and singularities on intensity ridge traversal and(More)
Recent contributions to the body of knowledge on traumatic brain injury (TBI) favor the view that multimodal neuroimaging using structural and functional magnetic resonance imaging (MRI and fMRI, respectively) as well as diffusion tensor imaging (DTI) has excellent potential to identify novel biomarkers and predictors of TBI outcome. This is particularly(More)
Blood vessels and other anatomic objects in the human body can be described as trees of branching tubes. The focus of this paper is the extraction of the branching geometry in 3D, as well as the extraction of the tubes themselves via skeletons computed as cores. Cores are height ridges of a graded measure of medial strength called medialness, which measures(More)
A 3D Partitioned Active Shape Model (PASM) is proposed in this paper to address the problems of the 3D Active Shape Models (ASM). When training sets are small. It is usually the case in 3D segmentation, 3D ASMs tend to be restrictive. This is because the allowable region spanned by relatively few eigenvectors cannot capture the full range of shape(More)
Almost all diseases affect blood vessel attributes (vessel number, radius, tortuosity, and branching pattern). Quantitative measurement of vessel attributes over relevant vessel populations could thus provide an important means of diagnosing and staging disease. Unfortunately, little is known about the statistical properties of vessel attributes. In(More)
We have developed a method for rigidly aligning images of tubes. This paper presents an evaluation of the consistency of that method for three-dimensional images of human vasculature. Vascular images may contain alignment ambiguities, poorly corresponding vascular networks, and non-rigid deformations, yet the Monte Carlo experiments presented in this paper(More)
The clinical recognition of abnormal vascular tortuosity, or excessive bending, twisting, and winding, is important to the diagnosis of many diseases. Automated detection and quantitation of abnormal vascular tortuosity from three-dimensional (3-D) medical image data would, therefore, be of value. However, previous research has centered primarily upon(More)
We describe and evaluate methods that create detailed vessel trees by linking vessels that have been segmented from magnetic resonance angiograms (MRA). The tree-definition process can automatically exclude erroneous vessel segmentations. The parent-child connectivity information provided by our vessel trees is important to both surgical planning and to(More)
Invited Paper Medial representation of a three-dimensional (3-D) object or an ensemble of 3-D objects involves capturing the object interior as a locus of medial atoms, each atom being two vectors of equal length joined at the tail at the medial point. Medial representation has a variety of beneficial properties, among the most important of which are 1) its(More)