Stephen O. Ojo

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Screening identified 2-(3-((4,6-dioxo-2-thioxotetrahydropyrimidin-5(2H)-ylidene)methyl)-2,5-dimethyl-1H-pyrrol-1-yl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbonitrile as an MDM2-p53 inhibitor (IC50 = 12.3 μM). MDM2-p53 and MDMX-p53 activity was seen for 5-((1-(4-chlorophenyl)-2,5-diphenyl-1H-pyrrol-3-yl)methylene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione(More)
A case of fatal haemorrhage is reported among 72 ultrasound (US) guided percutaneous fine-needle aspiration liver biopsies (FNAB) performed in the gastro- intestinal unit of Medicine Department in a tertiary hospital. The patient had primary hepatocellular carcinoma (PHCC) with advanced hepatic cirrhosis. Death was due to bleeding from liver nodule(More)
The study examined the effects of land acquisition for large scale farming on the performance; productivity and technical efficiency of small-scale farming in Nigeria. The primary data for the study were collected from 200 small-scale farmers selected using the multistage sampling technique, from three local government areas in Ondo State, Nigeria. The(More)
The traditional contract procurement has been widely criticized as an ineffective procurement method because it often involves time and cost overrun on construction projects. Yet the method is still being widely used in Nigeria most especially for the procurement of housing projects. It is suspected that this procurement method may not be ineffective in all(More)
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