Stephen Meier

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Loblolly pine (Pinus taeda) seedlings from three full-sib families were exposed to 0, 50, 100 or 150 ppb ozone (O(3)) (5 h/d, 5 d/week for 6 or 12 weeks). Soil water potential was maintained near pot capacity (-0.03 MPa) or soil was allowed to dry to approximately -1.0 MPa and resaturated. Chlorotic mottling and flecking of needles due to O(3) injury were(More)
Transgenic mice expressing human mutated superoxide dismutase 1 (SOD1) linked to familial forms of amyotrophic lateral sclerosis are frequently used as a disease model. We used the SOD1G93A mouse in a cross-breeding strategy to study the function of physiological prion protein (Prp). SOD1G93APrp-/- mice exhibited a significantly reduced life span, and an(More)
Considerable indirect evidence (1-4) and some direct evidence (5-8) indicate that glycosaminoglycans (GAG) promote certain types of morphogenesis and cell differentiat ion. Removal of basement m e m b r a n e by hyaluronidase disrupts salivary gland branching (2) and hyaluronate interferes with chondrocyte aggregat ion (5). On the positive side,(More)
The effect of vitamin A on the synthesis of acid mucopolysaccharides has been studiedin vitro in cell cultures of chick embryo sternal chondrocytes. Vitamin A produces a concentration-dependent inhibition of acid mucopolysaccharide synthesis. the inhibitory effect of vitamin A on acid mucopolysaccharide synthesis is not the result of a general cytotoxicity,(More)
Ooplasmic segregation in ascidians includes the movement of the myoplasm, a pigmented cytoplasmic region thought to be involved in the determination of the embryonic muscle and mesenchyme cell lineages, into the vegetal hemisphere of the egg. A myoplasmic cytoskeletal domain (MCD), composed of a cortical actin network (the PML) and an underlying filamentous(More)
Faced with continually coping with Moore's Law, computer-aided design (CAD) for integrated circuits is used to facing challenges in our ever-evolving design problem. Increasing device complexity is a perennial challenge and has led to several discontinuities in design methodology. Over the last decade deep submicron physical effects have significantly(More)
Explaining the evolution of sex and recombination is particularly intriguing for some species of eusocial insects because they display exceptionally high mating frequencies and genomic recombination rates. Explanations for both phenomena are based on the notion that both increase colony genetic diversity, with demonstrated benefits for colony disease(More)
Six-month-old loblolly pine (Pinus taeda) were grown for 15 weeks in two native soils amended with 0, 30, 60, 120, 240 or 480 mg kg(-1) Pb as PbCl2. Ectomycorrhizae were quantified, by morphotype, as the total number of tips per centimeter, and as the number of tips for each morphotype and for Cenococcum geophilum. Total numbers of non-ectomycorrhizal short(More)
Formation of ectomycorrhizae of red spruce (Picea rubens) grown in natural soil was measured after seedlings were exposed to 25 or 50 applications of simulated rain of pH 5.5, 3.5 or 2.5. Ectomycorrhizae were quantified as the total number of ectomycorrhizal tips per centimeter, and as the number of ectomycorrhizal tips for each morphotype and for(More)
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