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In the absence of legal enforcement procedures for the participants of an open e-marketplace, trust and reputation systems are central for resisting against threats from malicious agents. Such systems provide mechanisms for identifying the participants who disseminate unfair ratings. However, it is possible that some of the honest participants are also(More)
There has been a lot of research and development in the field of computational trust in the past decade. Much of it has acknowledged or claimed that trust is a good thing. We think it's time to look at the other side of the coin and ask the questions why is it good, what alternatives are there, where do they fit, and is our assumption always correct? We(More)
Recent clinical studies have identified an association between APOE 4 and cognitive deficits in patients with multiple sclerosis. We induced experimental autoimmune encephalomyelitis (EAE) in APOE knockout (KO) and human APOE 4 knockin (E4) mice to study the interaction of APOE and neuroinflammation on cognition. After EAE induction, KO and E4 showed(More)
A layered architecture for advanced collaborative environments has been developed to map the definition of a collaboration task from the requirements needed, to accomplish the task to the collaboration services that can be used to satisfy those needs, and to the technologies on which the services can be delivered. The architecture takes into account the(More)