Stephen M. J. Pollo

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Thermophiles are extremophiles that grow optimally at temperatures >45 °C. To survive and maintain function of their biological molecules, they have a suite of characteristics not found in organisms that grow at moderate temperature (mesophiles). At the cellular level, thermophiles have mechanisms for maintaining their membranes, nucleic acids, and other(More)
Temperature is one of the defining parameters of an ecological niche. Most organisms thrive within a temperature range that rarely exceeds ~30 °C, but the deep subsurface bacterium Kosmotoga olearia can grow over a temperature range of 59 °C (20–79 °C). To identify genes correlated with this flexible phenotype, we compared transcriptomes of K. olearia(More)
1 olearia, illuminate its adaptation to growth from 20ºC to 79ºC 2 Abstract 1 7 Temperature is one of the defining parameters of an ecological niche, and ambient temperature change is 1 8 a physiological challenge faced by all living cells. Most organisms are adapted to growing within a 1 9 temperature range that rarely exceeds ~ 30°C, but the deep(More)
Temperature affects cell function and survival. Most organisms are adapted to growing within a temperature range that rarely exceeds ~ 30°C, but the anaerobic thermophilic bacterium Kosmotoga olearia TBF 19.5.1 (phylum Thermotogae) is capable of growing over an extremely wide temperature range (20°C-79°C). We used transcriptomic and comparative genomic(More)
Stephen M. J. Pollo, Abigail A. Adebusuyi, Timothy J. Straub, Julia M. Foght, Olga 4 Zhaxybayeva and Camilla L. Nesbø 5 Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada 6 Department of Biological Sciences, Dartmouth College, Hanover, NH, USA 7 Department of Computer Science, Dartmouth College, Hanover, NH, USA 8 Centre for(More)
1 8 Temperature is an important parameter determining the distribution of organisms, and ambient 1 9 temperature change is a physiological challenge commonly faced by living cells. Most organisms 2 0 are adapted to growing within a temperature range that rarely exceeds ~ 30°C, but the anaerobic 2 1 thermophilic bacterium Kosmotoga olearia is capable of(More)
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