Learn More
BACKGROUND Follicular structures resembling germinal centres (GCs) that are characterized by follicular dendritic cell (FDC) networks have long been recognized in chronically inflamed tissues in autoimmune diseases, including the synovium of rheumatoid arthritis (RA). However, it is debated whether these ectopic structures promote autoimmunity and chronic(More)
There is good evidence to suggest that dose intensity is important when considering the effectiveness of adjuvant chemotherapy in patients with breast cancer. However, the development of chemotherapy-induced febrile neutropenia can lead to reduction in dose intensity and other treatment modifications, which may negatively affect patient outcomes. Febrile(More)
Efficient localisation is a highly desirable property for an autonomous navigation system. Weightless neural networks offer a real-time approach to robotics applications by reducing hardware and software requirements for pattern recognition techniques. Such networks offer the potential for objects, structures, routes and locations to be easily identified(More)
Half-field Offense (HFO) is a sub-task of Robocup 2D Simulated Soccer. HFO is a challenging, multi-agent machine learning problem in which a team of offense players attempt to manoeuvre the ball past a defending team and around the goalie in order to score. The agent's sensors and actuators are noisy, making the problem highly stochastic and partially(More)
Keepaway soccer is a challenging robot control task that has been widely used as a benchmark for evaluating multi-agent learning systems. The majority of research in this domain has been from the perspective of reinforcement learning (function approximation) and neu-roevolution. One of the challenges under multi-agent tasks such as keepaway is to formulate(More)
This work reports on an approach to direct policy discovery (a form of reinforcement learning) using genetic programming (GP) for the 3 by 3 by 3 Rubik's Cube. Specifically, a synthesis of two approaches is proposed: 1) a previous group theoretic formulation is used to suggest a sequence of objectives for developing solutions to different stages of the(More)
We explored the response of a panel of selected microRNAs (miRNAs) in neuroprotection produced by ischemic preconditioning. Hippocampal neuronal cultures were exposed to a 30-min oxygen–glucose deprivation (OGD). In our hands, this duration of OGD does not result in neuronal loss in vitro but significantly reduces neuronal death from a subsequent ‘lethal’(More)
—Powered wheelchair users may find operation in enclosed environments such as buildings difficult; a fundamental problem exists: wheelchairs are not much narrower than the doorway they wish to pass through. The ability to detect and pass through doorways represents a major current challenge for automated guided wheelchairs. We utilize a simple doorway(More)