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OBJECTIVE To define the region on human chromosome 19 carrying the gene for malignant hyperthermia susceptibility and to evaluate the use of flanking DNA markers in diagnosing susceptibility. DESIGN Prospective molecular genetic linkage studies in a large malignant hyperthermia pedigree. SETTING Irish malignant hyperthermia testing centre. SUBJECTS A(More)
In fishes, elevated levels of cortisol in eggs can have carry-over effects on phenotypic and performance traits early in life. How responses to elevations in egg cortisol differ among species remains poorly understood. Using wild populations of chum salmon (Oncorhynchus keta) and sockeye salmon (O. nerka), we investigated whether experimentally-elevated(More)
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