Stephen J. Fisher

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AIM To evaluate the effect of gender on clinical outcomes in people with type 2 diabetes mellitus (T2DM) receiving antidiabetes therapy. METHODS This is a pooled analysis from nine similarly designed phase 3 and 4 randomized, controlled studies evaluating insulin glargine and an active comparator (NPH insulin, insulin lispro, premixed insulin, oral(More)
OBJECTIVE Since the late 2000's, the creation of the National Institute for Health Research (NIHR) has transformed clinical research activity in the United Kingdom. This study sought to establish if there is a link between clinical research activity and overall NHS Trust performance. STUDY DESIGN Retrospective cohort study. METHODS Data for NHS Trust(More)
The medical profile of patients undergoing cataract extraction is reviewed, documenting preexisting and newly discovered conditions. This article concludes that significant medical conditions exist in this population and the elderly may require the support of facilities for inpatient-based elective cataract extraction despite the trend toward out-patient(More)
A comparative simultaneous evaluation of the Optimate and the TDX analyzers was performed according to guidelines proposed by the National Committee for Clinical Laboratory Standards. Statistically significant (P less than 0.05) better precision was demonstrated for the TDX analyzer with both commercial controls and patient pools. No statistically(More)
We wished to see if a maintained change in pressure at the baroreceptors leads to a maintained or a transient change in heart rate and total peripheral resistance, and if long-term changes in rate and resistance paralleled one another. In awake dogs with intact baroreceptors and complete atrioventricular block, ventricular rate was held alternately at high(More)
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