Stephen David Silberstein

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Chronic migraine (CM) is a prevalent and disabling neurological disorder. Few prophylactic treatments for CM have been investigated. OnabotulinumtoxinA, which inhibits the release of nociceptive(More)
OBJECTIVE To review evidence on the pharmacologic treatment of the child with migraine headache. METHODS The authors reviewed, abstracted, and classified relevant literature. Recommendations were(More)
BACKGROUND Calcitonin gene-related peptide (CGRP) is crucial in the pathophysiology of migraine. We assessed the safety, tolerability, and efficacy of ALD403, a genetically engineered humanised(More)