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Gene microarray technology is often used to compare the expression of thousand of genes in two different cell lines. Typically, one does not expect measurable changes in transcription amounts for a large number of genes; furthermore, the noise level of array experiments is rather high in relation to the available number of replicates. For the purpose of(More)
BACKGROUND The reports on efficacy of oral hydration treatment for the prevention of contrast-induced acute kidney injury (CIAKI) in elective radiological procedures and cardiac catheterization remain controversial. AIMS The objective of this meta-analysis was to assess the use of oral hydration regimen for prevention of CIAKI. MATERIALS AND METHODS(More)
BACKGROUND The association between elevated admission serum uric acid (SUA) and risk of in-hospital acute kidney injury (AKI) is limited. The aim of this study was to assess the risk of developing AKI in all hospitalized patients with various admission SUA levels. METHODS This is a single-center retrospective study conducted at a tertiary referral(More)
BACKGROUND The use of renin-angiotensin system (RAS) inhibitors in patients with chronic kidney disease, and especially in diabetic kidney disease, has been shown to provide renoprotective effects and slow progression to end-stage renal disease. However, this protective effect in kidney transplant patient populations is unclear. AIM The objective of this(More)
BACKGROUND Patients with medullary sponge kidney (MSK) commonly encounter recurrent nephrolithiasis. The existing knowledge on safety of donors with MSK has not been studied. METHODS We conducted a retrospective cohort study at a tertiary referral hospital to assess the outcomes of living kidney donors with MSK. All adults with MSK (N = 26) who underwent(More)
BACKGROUND The reported risk of coronary heart disease (CHD) in patients with a history of kidney stones is conflicting. AIMS The objective of this meta-analysis was to assess the association between a history of kidney stones and CHD risk. MATERIALS AND METHODS A literature search was performed using MEDLINE, EMBASE, and Cochrane Database of Systematic(More)
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