Stephanie Ramkumar

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Several human histo-blood groups are glycosphingolipids, including P/P1/P(k). Glycosphingolipids are implicated in HIV-host-cell-fusion and some bind to HIV-gp120 in vitro. Based on our previous studies on Fabry disease, where P(k) accumulates and reduces infection, and a soluble P(k) analog that inhibits infection, we investigated cell surface-expressed(More)
BACKGROUND Hypoglycemia secondary to ectopic insulin secretion of non-pancreatic tumors is rare. CASE PRESENTATION We describe a middle aged woman with recurrent hypoglycemia. On evaluation, she was detected to have hyperinsulinemic hypoglycemia and right sided renal mass lesion. 68Ga-Dotanoc and 99mTc-HYNICTOC scans confirmed the intrarenal mass to be of(More)
Aim To report a 6 years old girl who presented with sexual pre-cocity, multicystic ovaries and pituitary macroadenoma due to primary hypothyroidism. Methods We describe the clinical presentation, imaging findings, hormonal work-up and follow up of a child with sexual precocity, multicystic ovaries and pituitary macroadenoma due to primary hypothyroidism(More)
Aim To report a 13 year old girl with T2DM who had been initiated on insulin and the course of her glycemic status. Methods We describe a case of T2DM in a 13 year old girl – her clinical presentation, diagnosis and change in glycemic control over a period of 12 months. Results 13 year old presented with osmotic symptoms for 3 weeks duration. There was no(More)
Our previous genetic, pharmacological and analogue protection studies identified the glycosphingolipid, Gb(3) (globotriaosylceramide, Pk blood group antigen) as a natural resistance factor for HIV infection. Gb(3) is a B cell marker (CD77), but a fraction of activated peripheral blood mononuclear cells (PBMCs) can also express Gb(3). Activated PBMCs(More)
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