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Mir526b and Mir655 Promote Tumour Associated Angiogenesis and Lymphangiogenesis in Breast Cancer
The roles of cyclo-oxygenase (COX)-2 induced miR526b and miR655 in tumour-associated angiogenesis and lymphangiogenesis are examined and EP4 is considered as a potential therapeutic target to abrogate miRNA-induced angiogenic and lymphangaogenesis in breast cancer. Expand
miR526b and miR655 Induce Oxidative Stress in Breast Cancer
The dynamic functions of miR526b/miR655 in oxidative stress induction in breast cancer are established, and treatment with miRNA-conditioned media upregulates TXNRD1 in both MCF7 and HUVECs, indicating that oxidative stress also induces miRNA overexpression. Expand
Prostaglandin E2 promotes embryonic vascular development and maturation in zebrafish
The novel roles of PGE2 in promoting embryonic vascular maturation and angiogenesis in zebrafish are shown, which causes inflammation and cancer and its blockage results in serious physiological consequences. Expand