The use of real-time quantitative PCR (5' nuclease PCR assay) as a tool to study the gastrointestinal microflora that adheres to the colonic mucosa was evaluated. We developed primers and probes… (More)
TO THE EDITOR: Lead intoxication is a well known but rare cause of abdominal pain. Recognition is not difficult when there is an obvious history of occupational exposure to lead. Other causes of lead… (More)
PURPOSE
Infliximab has been reported to improve fistulizing Crohn's disease. Moreover, prompt healing of mucosal ulcers has been described. Whether fistulas disappear or remainders of fistulas… (More)
Crohn's disease is well known for its perianal complications, among which fistulas-in-ano are the most common abnormalities. Fistulas-in-ano in Crohn's disease tend to be complex and have a high… (More)
The gastrocolonic response consists of a prompt increase in colonic tone after a meal. With a barostat and a high compliant air-filled bag, it is possible to measure rectal tone by recording changes… (More)
Tonometric measurement of an elevatedintragastric PCO2 and a decreased calculatedgastric intramucosal pH can be used to detect gastricmucosal ischemia, provided that intraluminal productionof CO2… (More)
Continent appendio-cecostomy is a recently developed operation for the therapy of chronic constipation, refractory for other treatment modalities. Two patients are described in whom the operation led… (More)
 Crohn’s disease (CD) appears in forms so diverse that it has been hypothesized CD might be a syndrome, with different pathogenic mechanisms leading to the various clinical phenotypes. This may… (More)
Glucocorticosteroids (GCS) are effective intreatment of inflammatory bowel disease (IBD), but alsohave unwanted systemic side effects. Here, we describethe effects of budesonide and dexamethasone on… (More)
The relationship between electrophoretic pepsinogen A (PGA) patterns from urine and gastric mucosa was studied in healthy volunteers and in patients with various gastric disorders. Discrepancies… (More)