Stella W. Pang

Learn More
Cells are known to be surrounded by nanoscale topography in their natural extracellular environment. The cell behavior, including morphology, proliferation, and motility of bovine pulmonary artery smooth muscle cells (SMC) were studied on poly(methyl methacrylate) (PMMA) and poly(dimethylsiloxane) (PDMS) surfaces comprising nanopatterned gratings with 350(More)
Tissue engineering seeks to develop functional tissues in a biomimetic environment in vitro. As the extracellular environment in vivo is composed of numerous nanostructures, fabrication of nanostructured substrates will be valuable for tissue engineering applications. In this article, we report a simple nanoimprint lithography (NIL) process to pattern(More)
— A simple process has been developed which combines thick single-crystal Si micromechanical devices with a bipolar complimentary metal–oxide–semiconductor (BiCMOS) integrated circuit process. This merged process allows the integration of Si mechanical resonators as thick as 11 m with any integrated circuit process with the addition of only a single masking(More)
Control of cell migration is important in numerous key biological processes, and is implicated in pathological conditions such as cancer metastasis and inflammatory diseases. Many previous studies indicated that cell migration could be guided by micropatterns fabricated on cell culture surfaces. In this study, we designed a polydimethylsiloxane cell culture(More)
A combinatorial approach was used to present primary neurons with a large library of topographical features in the form of micropatterned substrate for high-throughput screening of physical neural-guidance cues that can effectively promote different aspects of neuronal development, including axon and dendritic outgrowth. Notably, the neuronal-guidance(More)
This paper discusses the development of a high-accuracy endpointing algorithm for the emitter etch of a heterojunction bipolar transistor HBT. Fabrication of high-performance HBT's using self-aligned base-emitter processes requires etching through the emitter layer and stopping with very high accuracy on the base layer. The lack of selectivity in dry(More)
The profile shape and the flow behavior of polymer nanoscale gratings made by a thermal nanoimprint process are precisely examined using visible light angular scatterometry. Nanoimprinted poly͑methyl methacrylate͒ ͑PMMA͒ lines with 60– 800 nm width, 100– 200 nm height, and varied residual thicknesses of 70– 400 nm have been investigated using this optical(More)
We investigated a dielectric transmission line consisting of three dielectric substrate layers for millimeter-wave (mmW) applications. This line is referred to as a narrowed dielectric microstrip line (N-DML). The effective dielectric constant method is used to analyze the propagation characteristics of the N-DML. The result of the analysis of the(More)
On a microgrooved substrate, cells migrate along the pattern, and at random positions, reverse their directions. Here, we demonstrate that these reversals can be controlled by introducing discontinuities to the pattern. On "V-shaped grating patterns", mouse osteogenic progenitor MC3T3-E1 cells reversed predominately at the bends and the ends. The patterns(More)