Steffen Oswald

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A major function of the cell-to-cell adhesion molecule E-cadherin is the maintenance of cell adhesion and tissue integrity. E-cadherin deficiency in tumours leads to changes in cell morphology and motility, so that E-cadherin is considered to be a suppressor of invasion. In this study we investigated the functional consequences of three tumour-associated(More)
One task in risk assessment of engineered nanoparticles is toxicological studies. A suitable interpretation of these investigations demands a comprehensive physical-chemical characterization. Here, we present an approach to gain well-dispersed nanoparticles in physiological media. Therefore, a step-by-step procedure is demonstrated on two different tungsten(More)
AIM In this paper, carbon nanotubes (CNTs) are presented as feasible carriers for carboplatin, a therapeutic agent for cancer treatment. The drug was introduced into CNTs to demonstrate that they are suited as nanocontainers and nanocarriers and can release the drug to initialize its medical virtue. METHOD The filling was accomplished by a wet-chemical(More)
Producing sterile glass surfaces is of great importance for a wide range of laboratory and medical applications, including in vitro cell culture and tissue engineering. However, sterilization may change the surface properties of glass and thereby affect its use for medical applications, for instance as a substrate for culturing cells. To investigate(More)
Calcium and phosphorus storage in a thin layer of titanium surface was achieved by ion implantation. We study the reactivity of this surface in response to a hydrothermal treatment. The incipient implanted species are observed to convert to Ca(2+) and PO(4)(3-), the precursors for generating calcium phosphate polymorphs. Hydroxyapatite is formed from these(More)
We have introduced a facile strategy to fabricate sandwich-stacked SnO2/Cu hybrid nanosheets as multichannel anodes for lithium-ion batteries applying rolled-up nanotechnology with the use of carbon black as intersheet spacer. By employing a direct self-rolling and compressing approach, a much higher effective volume efficiency is achieved as compared to(More)
Hierarchically designed SiOx /SiOy rolled-up bilayer nanomembranes are used as anodes for lithium-ion batteries. The functionalities of the SiO(x,y) layers can be engineered by simply controlling the oxygen content, resulting in anodes that exhibit a reversible capacity of about 1300 mA h g(-1) with an excellent stability of over 100 cycles, as well as a(More)
Samples of low modulus beta-type Ti40Nb and cp2-Ti were chemically treated with 98% H2 SO4 + 30% H2 O2 (vol. ratio 1:1) solution. Surface analytical studies conducted with HR-SEM, AFM, and XPS identified a characteristic nanoroughness of the alloy surface related with a network of nanopits of ∼25 nm diameter. This is very similar to that obtained for(More)