Steffen Hüttner

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Streptomyces arenae is able to grow on acetate or ethanol as the sole carbon source. The metabolic pathway used for gluconeogenesis from C2 compounds in streptomycetes has not yet been characterized. In the course of a sequencing project we identified the gene for malate synthase (aceB), a key enzyme in the glyoxylate cycle in S. arenae. The gene was cloned(More)
New deep-sequencing technologies are applied to transcript sequencing (RNA-seq) for transcriptomic studies. However, current approaches are based on the availability of a reference genome sequence for read mapping. We present Passage, a method for efficient read clustering in the absence of a reference genome that allows sequencing-based comparative(More)
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