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Journals and Conferences
I'm your Venus: the crystal structure of the human methylamine-induced form of α(2)-macroglobulin (α(2)M) shows its large central cavity can accommodate two medium-sized proteinases. Twelve major entrances provide access for small substrates to the cavity and the still-active trapped "prey". The structure unveils the molecular basis of the unique "venus… (More)
The FFT calculation of spherical harmonics, Wigner D matrices and rotation function has been extended to all angular variables in the AMoRe molecular replacement software. The resulting code avoids singularity issues arising from recursive formulas, performs faster and produces results with at least the same accuracy as the original code. The new code aims… (More)
A method for finding the center of cryo-EM images which correspond to the projections of a symmetric 3D structure, based on mathematical properties of symmetry adapted functions and the Fourier-Bessel transform, is presented. It is a model independent one-step procedure with no parameters to be chosen by the user. The proposed method is tested in one… (More)
The Mumford class κ1 on Mg,0 was shown to be proportional to the cohomology class [ωWP ] of the Weil-Petersson form by Wolpert in [WO]. Furthermore he showed that the restriction of this class to any component of the compactyfying divisor coincides with the corresponding Weil-Petersson class. Arbarello and Cornalba introduced classes κ1 on Mg,n, proved a… (More)
We discuss the variational properties of the unique conical metric of constant curvature −1 associated to a compact Riemann surface together with a weighted divisor. 2005 Elsevier Inc. All rights reserved.
Many animal and plant viruses rely on vectors for their transmission from host to host. Grapevine fanleaf virus (GFLV), a picorna-like virus from plants, is transmitted specifically by the ectoparasitic nematode Xiphinema index. The icosahedral capsid of GFLV, which consists of 60 identical coat protein subunits (CP), carries the determinants of this… (More)
An account is given of the latest developments of the AMoRe package: new rotational search algorithms, exploitation of noncrystallographic symmetry, generation and use of ensemble models and interactive graphical molecular replacement.
Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (EC 220.127.116.11) is a central enzyme in the purine recycling pathway. Parasitic protozoa of the order Kinetoplastida cannot synthesize purines de novo and use the salvage pathway to synthesize purine bases, making this an attractive target for antiparasitic drug design. The glycosomal HGPRT from Leishmania… (More)
In the past decades the study of pluri-potential theory and of its applications played a central role in complex analysis in several variables. In particular, since the basic work of Siciak  and Bedford and Taylor ,  a great effort was made to understand the complex MongeAmpère operator and the associated generalized Dirichlet problems (for… (More)
We show that for every smooth generic projective hypersurface X ⊂ P, there exists a proper subvariety Y ( X such that codimX Y ≥ 2 and for every non constant holomorphic entire map f : C → X one has f(C) ⊂ Y , provided degX ≥ 2 5 . In particular, we obtain an effective confirmation of the Kobayashi conjecture for threefolds in P.