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  • Christian Ludwig, John M. Easton, +9 authors Mark R. Viant
  • Biology
  • Metabolomics
  • 2011 (First Publication: 1 February 2012)
  • Public databases of NMR spectra of low molecular weight metabolites must be constructed to remove the major bottleneck of metabolite identification and quantification in the analysis of metabolomicsContinue Reading
    Abstract Background Sacituzumab govitecan (SG) is an antibody drug conjugate (ADC) that targets Trop-2 for the selective delivery of SN-38 to tumors. SG carries SN-38, a topoisomerase inhibitorContinue Reading
  • Andrew Brenner, John R. Floyd, Prathiba Surapaneni, Vinu Madhusudanan-Kunnuparampil, Stefano Tiziani
  • Medicine
  • Neuro-oncology Advances
  • 2019 (First Publication: 1 August 2019)
  • Abstract Sacituzumab govitecan (SG) is an antibody drug conjugate (ADC) that targets Trop-2 for the selective delivery of SN-38 to tumors. SG carries SN-38, a topoisomerase inhibitor active in theContinue Reading
  • Andrew Brenner, John R. Floyd, +5 authors Stefano Tiziani
  • Medicine
  • 2014 (First Publication: 1 November 2014)
  • BACKGROUND: Hypoxia is implicated in the pathogenesis of glioblastoma multiforme (GBM), and greater hypoxic burden is associated with poorer outcomes in GBM. Treatment with bevacizumab (BEV) mayContinue Reading