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High levels of propionic acid (PPA) comparable to those of human propionic acidemia were achieved in blood (1-5 mmol/l) and brain (1 micromol/g) of rats by administering saline-buffered propionate (pH 7.4) subcutaneously twice a day from the 6th to the 28th day of life. PPA doses ranged from 1.44 to 1.92 micromol/g body weight as a function of animal age.(More)
Elevated levels of propionate comparable to those of human propionic acidaemia were achieved in the blood of young rats by injecting subcutaneously buffered propionic acid (PPA) twice a day at 8-h intervals from the 6th to the 28th day of life. A matched group of animals (controls) was treated with the same volumes of saline. The animals were weighed and(More)
Taxonomic arrangement of Hypnum species has been controversial since the beginning of the nineteenth century. The molecular pattern and phylogenetic relationships within the Hypnum cupressiforme complex, in relation to other pleurocarps species, were investigated by study of nuclear ribosomal ITS1/ITS2 and chloroplast trnLUAA intron sequences. Seven Hypnum(More)
T he effects of MK-801 on retinal laser injury reported by Solberg et al. 1 in the June 1997 issue of IOVS constitute an interesting finding. As in neuronal injuries caused by ischemia or trauma, a treatment for accidental laser-induced retinal injury will become clinically useful only if it is effective when used after the insult. In neuronal injury, the(More)
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