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The identity of cells that establish the hematopoietic microenvironment (HME) in human bone marrow (BM), and of clonogenic skeletal progenitors found in BM stroma, has long remained elusive. We show that MCAM/CD146-expressing, subendothelial cells in human BM stroma are capable of transferring, upon transplantation, the HME to heterotopic sites, coincident(More)
We investigated whether observation of actions reproduced in three-dimensional virtual reality would engage perceptual and visuomotor brain processes different from those induced by the observation of real hand actions. Participants were asked to passively observe grasping actions of geometrical objects made by a real hand or by hand reconstructions of(More)
An approximating neural model, called hierarchical radial basis function (HRBF) network, is presented here. This is a self-organizing (by growing) multiscale version of a radial basis function (RBF) network. It is constituted of hierarchical layers, each containing a Gaussian grid at a decreasing scale. The grids are not completely filled, but units are(More)
Retinitis pigmentosa (RP) is a group of inherited disorders affecting 1 in 3000-7000 people and characterized by abnormalities of the photoreceptors (rods and cones) or the retinal pigment epithelium of the retina which lead to progressive visual loss. RP can be inherited in an autosomal dominant, autosomal recessive or X-linked manner. While usually(More)
Social virtual worlds such as Second Life (SL) are digital representations of the real world where human-controlled avatars evolve and interact through social activities. Understanding the characteristics of virtual worlds can be extremely valuable in order to optimize their design. In this paper, we perform an extensive analysis of SL. We exploit standard(More)
PCTAIRE-1 is a member of the cyclin-dependent kinase (cdk) family whose function is unknown. We examined the pattern of PCTAIRE-1 protein expression in a number of normal and transformed cell lines of various origins and found that the kinase is ubiquitous. Indirect immunofluorescence indicated that PCTAIRE-1 exhibits cytoplasmic distribution throughout the(More)
—A procedure for the real-time construction of three-dimensional (3-D) multiscale meshes from not evenly sampled 3-D points is described and discussed in this paper. The process is based on the connectionist model named hierarchical radial basis functions network (HRBF), which has been proved effective in the reconstruction of smooth surfaces from sparse(More)
—A portable and flexible system for three-dimensional (3-D) scanning is here presented. It is constituted of four main modules. The first module is devoted to the acquisition of a set of 3-D points over the surface through laser scanning (digitization). The second module reconstructs a continuous 3-D surface, filtering the measurement noise. Whenever(More)
PURPOSE To characterize the expression of the visual system homeobox gene (VSX1) in human corneal keratocytes both in vitro and in vivo. METHODS The expression of VSX1 was evaluated through semiquantitative RT-PCR, immunofluorescence and in situ hybridization both in corneas (either freshly obtained or wounded) and in collagenase/hyaluronidase-isolated(More)