Stefanie Seiler

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BACKGROUND Parkinson's disease (PD) is characterized by the progressive degeneration of the nigrostriatal dopaminergic pathway and the emergence of rigidity, tremor, and bradykinesia. Accumulating evidence indicates that PD is also accompanied by nonmotor symptoms including cognitive deficits, often manifested as impaired visuospatial memory. METHODS We(More)
BACKGROUND Angiogenesis and vascular remodelling are crucial events in tissue repair mechanisms promoted by cell transplantation. Current evidence underscores the importance of the soluble factors secreted by stem cells in tissue regeneration. In the present study we investigated the effects of paracrine factors derived from cultured endothelial progenitor(More)
Number of pages: 317 pages Thank you for downloading soi design analog memory and digital techniques. Maybe you have knowledge that, people have look numerous times for their favorite novels like this soi design analog memory and digital techniques, but end up in infectious downloads. Rather than enjoying a good book with a cup of coffee in the afternoon,(More)
The myelin-associated protein Nogo-A is among the most potent neurite growth inhibitors in the adult CNS. Recently, Nogo-A expression was demonstrated in a number of neuronal subpopulations of the adult and developing CNS but at present, little is known about the expression of Nogo-A in the nigrostriatal system, a brain structure severely affected in(More)
The myelin-associated protein Nogo-A and its receptor Nogo-receptor 1 (NgR1) are known as potent growth inhibitors of the adult central nervous system (CNS). Nogo-A is mostly expressed on the surface of oligodendrocytes, but is also found in neurons of the adult and developing CNS. This observation suggests that Nogo-A serves additional functions in the(More)
Number of pages: 111 pages Thank you for reading excellence without a soul does liberal education have a future. Maybe you have knowledge that, people have look numerous times for their favorite books like this excellence without a soul does liberal education have a future, but end up in malicious downloads. Rather than enjoying a good book with a cup of(More)
Thank you very much for downloading ambient intelligence for scientific discovery foundations theories and systems. Maybe you have knowledge that, people have search numerous times for their favorite readings like this ambient intelligence for scientific discovery foundations theories and systems, but end up in infectious downloads. Rather than reading a(More)
Transplantation of fetal human ventral mesencephalic (VM) dopaminergic neurons into the striatum is a promising strategy to compensate for the characteristic dopamine deficit observed in Parkinson's disease (PD). This therapeutic approach, however, is currently limited by the high number of fetuses needed for transplantation and the poor survival and(More)
Nogo-A is a myelin associated protein and one of the most potent neurite growth inhibitors in the central nervous system. Interference with Nogo-A signaling has thus been investigated as therapeutic target to promote functional recovery in CNS injuries. Still, the finding that Nogo-A presents a fairly ubiquitous expression in many types of neurons in(More)