Stefanie Linss

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INTRODUCTION Mesenchymal stem cells (MSC) are highly attractive for use in cartilage regeneration. To date, MSC are usually recruited from subchondral bone marrow using microfracture. Recent data suggest that isolated cells from adult human articular cartilage, which express the combination of the cell-surface markers CD105 and CD166, are multi-potent(More)
INTRODUCTION Current therapies for articular cartilage defects fail to achieve qualitatively sufficient tissue regeneration, possibly because of a mismatch between the speed of cartilage rebuilding and the resorption of degradable implant polymers. The present study focused on the self-healing capacity of resident cartilage cells in conjunction with(More)
Die begrenzte Regenerationsfähigkeit von hyalinem Gelenkknorpel erfordert detaillierte Studien zur Gewebsintegration von Knorpeltransplantaten mittels aussagekräftiger, aber zeitlich bzw. finanziell aufwändiger und z. T. ethisch problematischer Tiermodelle. Eine Alternative hierzu sind In-vitro-Testssysteme für Implantatmaterialien. Diese Studie beschreibt(More)
Introduction: Current therapies for articular cartilage defects fail to achieve qualitatively sufficient tissue regeneration, possibly because of a mismatch between the speed of cartilage rebuilding and the resorption of degradable implant polymers. The present study focused on the self-healing capacity of resident cartilage cells in conjunction with(More)
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