Stefani T Rudnick

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The plo gene, encoding the Arcanobacterium pyogenes cholesterol-dependent cytolysin, pyolysin (PLO), was localized to a 2.7-kb genomic islet of reduced %G+C content and alternate codon usage frequency. This islet, conserved among isolates from diverse hosts and geographical locations, separated the housekeeping genes smc and ftsY, which are found adjacent(More)
Arcanobacterium pyogenes is an opportunistic pathogen of a number of important livestock species, and usually infects from an endogenous, commensal source. Thus, as with other normal flora opportunistic pathogens, the regulation of A. pyogenes virulence factors is likely important during both commensal and pathogenic interactions with the host. The aim of(More)
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