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  • Özgür Sahin, Holger Fröhlich, +11 authors Dorit Arlt
  • Biology, Medicine, Computer Science
  • BMC Systems Biology
  • 2008 (First Publication: 1 January 2009)
  • BackgroundIn breast cancer, overexpression of the transmembrane tyrosine kinase ERBB2 is an adverse prognostic marker, and occurs in almost 30% of the patients. For therapeutic intervention, ERBB2 isContinue Reading
  • Sarah Jurmeister, Marek Baumann, +6 authors Özgür Şahin
  • Biology, Medicine
  • Molecular and cellular biology
  • 2012 (First Publication: 1 February 2012)
  • MicroRNA-200c (miR-200c) has been shown to suppress epithelial-mesenchymal transition (EMT), which is attributed mainly to targeting of ZEB1/ZEB2, repressors of the cell-cell contact proteinContinue Reading
  • Sarah Barthelmeß, Helene Geddert, +8 authors Florian Haller
  • Biology, Medicine
  • The American journal of pathology
  • 2014 (First Publication: 1 April 2014)
  • Recurrent somatic fusions of the two genes, NGFI-A-binding protein 2 (NAB2) and STAT6, located at chromosomal region 12q13, have been recently identified to be presumable tumor-initiating events inContinue Reading