Stefan St Kostianev

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BACKGROUND Smoking may cause inflammation of the airways and impairment of lung function. To determine the relationship between the type and degree of airways inflammation and the decline in lung function, leucocytes in the sputum of smokers and ex-smokers were examined. METHODS Forty six smokers and ex-smokers of median age 64 years (25%; 75% percentiles(More)
Sixty children, in the age span 6-17 years originally divided into two groups, matched by age, sex and height--30 obese subjects [15 girls/15 boys; body mass index (BMI) = 27.4 +/- 4.5 m kg-2; ideal body weight (IBW) range = 122-185%] and 30 controls (BMI = 18.8 +/- 2.7 m kg-2) performed incremental treadmill exercise test. Perceived exertion was assessed(More)
Oxygen uptake efficiency slope (OUES) is an index meant to provide an objective measure of cardiopulmonary function at submaximal exercise. The aim was to study the exercise performance and OUES in obese children performing standardized exercise. Sixty children aged 6-17 years performed incremental treadmill exercise test. They were divided into two groups(More)
Inspiratory flow limitation (FL) during sleep has previously been reported both in obstructive sleep apnoea (OSA) patients and heavy snorers (HS). Recent results from this laboratory have shown the occurrence both of inspiratory and expiratory flow limitation during muscular relaxation in awake healthy subjects and OSA patients. In this study, we have(More)
BACKGROUND Research on the diverse aspects of exercise performance in childhood in the past 20 years has included an increase in the study of perceived exertion. OBJECTIVE The aim of this study was to compare children's ratings of effort perception by means of the Borg Category-Ratio Perceived Exertion (CR-10) Scale and a pictorial version of the(More)
1. The impact of ventilatory efficiency on reduced exercise capacity and recovery oxygen kinetics has not been addressed in cirrhotic patients. The aim of the present study was to investigate exercise performance and ventilatory efficiency in patients with mild and moderate liver cirrhosis (LC). 2. Nineteen male non-hypoxic patients with LC (age 51.3 +/-(More)
The aim of this paper is to study the differences in ventilatory response to exercise in prepubertal and pubertal children. One hundred children in the following groups: 10-year-olds (25 boys/25 girls) and 13-year-olds (25 boys/25 girls) performed sub maximal treadmill stress test, using modified Balke protocol. All of them went through complex pulmonary(More)
UNLABELLED Thalassemia major is associated with impaired exercise tolerance because of the severe anemia and cardiopulmonary dysfunction characteristic of the condition. OBJECTIVE To assess the exercise performance in thalassemic children before and two hours after hemotransfusion. PATIENTS AND METHODS The study included eleven children with thalassemia(More)
INTRODUCTION The therapeutic modality for the treatment of COPD depends on the proper determination of all factors that may have an effect on the course and prognosis of the disease. AIM To assess the prognostic role of maximal inspiratory pressure (PImax) and a large group of lung function parameters in patients with COPD followed up over a period of(More)