Stefan Scheingraber

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BACKGROUND Changes in acid-base balance caused by infusion of a 0.9% saline solution during anesthesia and surgery are poorly characterized. Therefore, the authors evaluated these phenomena in a dose-response study. METHODS Two groups of 12 patients each who were undergoing major intraabdominal gynecologic surgery were assigned randomly to receive 0.9%(More)
BACKGROUND Preoperative acute normovolemic hemodilution (ANH) is an excellent model for evaluating the effects of different colloid solutions that are free of bicarbonate but have large chloride concentrations on acid-base equilibrium. METHODS In 20 patients undergoing gynecologic surgery, ANH to a hematocrit of 22% was performed. Two groups of 10(More)
UNLABELLED Acid base status during transurethral resection of the prostate (TURP) has been almost neglected. We therefore measured the acid base status and interpreted the observed changes according to the Stewart approach. The Stewart model focuses more on the influence of serum electrolyte concentrations on acid base changes than does the conventional(More)
High concentrations of levofloxacin in soft tissues and body fluids, including gallbladder and bile, have been repeatedly reported, but no study on its penetration into human liver tissue after single-shot application has yet been published. Levofloxacin 500 mg was administered intravenously to 28 patients scheduled for liver resection. Blood samples were(More)
BACKGROUND Monitoring of peritoneal cytokine concentrations of tumor necrosis factor (TNF)-alpha was recommended for early detection of severe postoperative complications. In the present study the clinical application of cytokine monitoring was examined in the treatment course of severe peritonitis. METHODS Nineteen patients with secondary peritonitis(More)
To evaluate changes in acid-base balance following bolus infusions of a 20% albumin solution. Randomized prospective study in a university hospital. Two groups of eight patients each undergoing gynecological surgery. Patients were randomly assigned to receive either 0.9% saline or lactated Ringer’s solution. At the end of surgery two boluses of 0.5 g/kg(More)
In einer halb retro- und halb prospektiven multizentrischen Studie in der Region München im Jahre 1992 wurden 80% von 104 Patienten mit schwerem SHT von einem Notarzt am Unfallort versorgt. Die mittlere Eintreffzeit betrug 8,2 Minuten. 70% der Patienten wurden direkt vom Unfallort in ein Zentrum mit neurochirurgischer Fachabteilung transportiert, weit mehr(More)
BACKGROUND/AIMS Non-invasive measurement of indocyanine green plasma disappearance rate (PDR(ICG)) is supposed to be an accurate liver function parameter. However, its value compared to conventional markers like bilirubin and prothrombin time (PT) is unclear. The authors therefore prospectively determined PDR(ICG) and bilirubin and PT and recorded the(More)
BACKGROUND/PURPOSE The aim of this study was to compare the short-form (SF-) 36 as a general instrument and the gastrointestinal quality of life index (GIQLI) as a disease-specific instrument in patients after pancreatic surgery. METHODS The questionnaires were sent to patients receiving pancreatic surgery over a time period of three years. Patients were(More)
Experimental and clinical evidence suggests that gender has a profound influence on outcome after inflammatory hits caused by such events as trauma. We conducted this prospective clinical study to evaluate the influence of gender on the release of pro- and anti-inflammatory cytokines in the circulation and after lipopolysaccharide (LPS) ex vivo stimulation.(More)