Stefan Schäfer

Learn More
Instruction selection is a compiler optimisation that translates the intermediate representation of a program into a lower intermediate representation or an assembler program. We use the SSA form as an intermediate representation for instruction selection. Patterns are used for translation and are expressed as production rules in a graph grammar. The(More)
Today's most challenging application of computer graphics is the rendering of real scale scenes at photorealistic quality. As this task needs a lot of computing resources, numerous techniques have been applied to speed up rendering, one of these being parallel processing. This paper presents our approach to the efficient parallelization of different(More)
INTRODUCTION The trend towards submillisievert CT scans leads to a higher dose fraction of localizer radiographs in CT examinations. The already existing technical capabilities make dose optimization of localizer radiographs worthwhile. Modern CT scanners apply automatic exposure control (AEC) based on attenuation data in such a localizer. Therefore not(More)
Human neutrophil elastase (HNE) is a key protease for matrix degradation. High HNE activity is observed in inflammatory diseases. Accordingly, HNE is a potential target for the treatment of pulmonary diseases such as chronic obstructive pulmonary disease (COPD), acute lung injury (ALI), acute respiratory distress syndrome (ARDS), bronchiectasis (BE), and(More)
  • Friedrich Ghofrani, Andreas E Grimminger, Stefan Schäfer Busch, Soni S Nikolova, Norbert Pullamsetti, Eva Weissmann +23 others
  • 2008
Background—Inhibition of tyrosine kinases, including platelet-derived growth factor receptor, can reduce pulmonary arterial pressure in experimental and clinical pulmonary hypertension. We hypothesized that inhibition of the serine/threonine kinases Raf-1 (also termed c-Raf) and b-Raf in addition to inhibition of tyrosine kinases effectively controls(More)
Reduced exercise capacity is a key symptom and an independent determinant of mortality in patients with heart failure. We analyzed the running activity of hamsters with cardiac dysfunction after myocardial infarction. In 39 male Syrian hamsters aged 10 to 12 weeks, a myocardial infarction (MI) was produced by permanent ligation of the left coronary artery.(More)
This paper introduces the Internet Operating Platform (IOP), an enterprise framework for large scale software development. In addition to obeying to important standards (UML, XML, Java) an enterprise framework has to fulfil three basic requirements. First of all, it has to be broad and needs an elaborate architecture complementing standards and technologies(More)
  • 1