Stefan Rasche

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BACKGROUND Levosimendan is a novel drug used for inotropic support in heart failure, but its efficacy in local anesthetic-induced myocardial depression is not known. Therefore, we investigated the effects of levosimendan on the negative inotropic response to ropivacaine in isolated heart preparations of guinea pigs. METHODS Action potentials and force of(More)
Camera-based photoplethysmography is a contactless mean to assess vital parameters, such as heart rate and respiratory rate. In the field of camera-based photoplethysmography, blind source separation (BSS) techniques have been extensively applied to cope with artifacts and noise. Despite their wide usage, there is no consensus that common BSS approaches(More)
Camera-based photoplethysmography (cbPPG) is a novel measuring technique that permits the remote acquisition of cardiovascular signals using video cameras. Research still lacks in fundamental studies to reach a deeper technical and physiological understanding. This work analyzes the employment of polarization filtration to (i) assess the gain for the signal(More)
Inhalation of perfluorohexane vapor (PFH) and high-frequency oscillatory ventilation (HFOV) both have been shown to improve lung function in acute lung injury (ALI). Their combination implies synergistic action. The authors investigated technical aspects of PFH vaporization during HFOV and effects on gas exchange in a pilot study of experimental ALI.(More)
The concept of scarless surgery aims at further minimization of diagnostic and therapeutic interventions. Based on the success of flexible gastroenterological endoscopy and laparoscopic surgery, it combines their advantageous approaches in a synergistic manner. Animal experiments have achieved encouraging results in respect to the feasibility of various(More)
Das Konzept der narbenlosen Eingriffe basiert auf der Vorstellung, die Invasivität diagnostischer und therapeutischer Eingriffe konsequent weiter zu minimieren. Sie baut auf den Erfolgen der flexiblen gastroenterologischen Endoskopie und der minimal-invasiven Chirurgie auf und versucht, deren Vorteile synergistisch zu kumulieren. Tierexperimente haben(More)
© The Author(s) 2017. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the(More)
Blind source separation (BSS) aims at separating useful signal content from distortions. In the contactless acquisition of vital signs by means of the camera-based photoplethysmogram (cbPPG), BSS has evolved the most widely used approach to extract the cardiac pulse. Despite its frequent application, there is no consensus about the optimal usage of BSS and(More)
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