Stefan Paul Moenig

Learn More
Abstract Purpose. The incidence of adenocarcinoma of the esophagus is increasing in most Western industrialized nations especially in white males. The impact of vitamins on the development of squamous cell carcinoma (SCC) and adenocarcinoma (AC) of the esophagus has not been elucidated. The goal of this pilot-study was to analyze the influence of daily(More)
Authors M. Moehler, S.-E. Al-Batran, T. Andus, M. Anthuber, J. Arends, D. Arnold, D. Aust, P. Baier, G. Baretton, J. Bernhardt, H. Boeing, E. Böhle, C. Bokemeyer, J. Bornschein, W. Budach, E. Burmester, K. Caca, W. A. Diemer, C. F. Dietrich, M. Ebert, A. Eickhoff, C. Ell, J. Fahlke, H. Feußner, R. Fietkau, W. Fischbach, W. Fleig, M. Flentje, H. E. Gabbert,(More)
AIMS The significance of MUC1, MUC2 and sialylated Lewis blood group antigens as prognostic markers in colorectal adenocarcinoma was investigated in a large series of patients because previous investigations revealed inconsistent results due to unrelated tumour samples from different patient groups and methodological differences. METHODS AND RESULTS(More)
The purpose of this study was to clarify the relationship of the immunohistochemical expression of c-met, p53 and p21 with clinicopathological parameters and prognosis in gastric carcinomas. We analyzed specimens from 114 gastric cancer patients (median age 64 years, range: 33-86) who underwent gastrectomy with lymphadenectomy. Specimens were categorized(More)
The expression of MUC1 and MUC2 mucin peptide core antigens in gastric carcinomas was studied by immunohistochemistry to determine correlations with TNM stage and histo-pathological classifications as well as a possible prognostic impact. Paraffin-embedded specimens from 128 gastric carcinomas with a minimal follow-up of 5 years were immunostained. In(More)
AIMS One important step in tumour invasion is the penetration of the basement membrane. Matrix metalloproteinases (MMPs) play a key role in the migration of normal and malignant cells through the basement membrane. The aim of this study was to investigate correlations between matrix metalloproteinase 2 (MMP-2) immunoreactivity and currently used(More)
OBJECTIVE The purpose of this study was to evaluate the frequency of lymph node metastasis according to the depth of tumor infiltration of the mucosa and submucosa. BACKGROUND DATA Currently some endoscopists extend the indication for endoscopic mucosal resection in gastric cancer to the submucosa. However, the decision between endoscopic mucosectomy or(More)
BACKGROUND AND OBJECTIVES The indication for splenectomy in proximal gastric cancer remains controversial. Splenectomy is performed because of possible lymph node metastasis of the splenic hilus or infiltration/metastasis of the spleen. The purpose of this study was to investigate the frequency of lymph node metastasis to the splenic hilus and metastasis to(More)
Remarkable efficacy of immune checkpoint inhibition has been reported for several types of solid tumors and early studies in gastric adenocarcinoma are promising. A detailed knowledge about the natural biology of immune checkpoints in gastric adenocarcinoma is essential for clinical and translational evaluation of these drugs. This study is a comprehensive(More)
Die aktuelle S3-Leitlinie zur Diagnostik und Therapie des Magenkarzinoms einschließlich der Adenokarzinome des ösophagogastralen Übergangs beschreibt die bestmöglichen Versorgungsmodalitäten basierend auf hoher Evidenz und interdisziplinärem Konsens verschiedener medizinischer Fachgebiete. Die Ösophagogastroduodenoskopie mit Entnahme multipler Biopsien ist(More)