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PURPOSE To evaluate the validity of different approaches to determine the signal-to-noise ratio (SNR) in MRI experiments with multi-element surface coils, parallel imaging, and different reconstruction filters. MATERIALS AND METHODS Four different approaches of SNR calculation were compared in phantom measurements and in vivo based on: 1) the(More)
OBJECTIVES The aim of this prospective study was to evaluate the diagnostic performance of magnetic resonance imaging (MRI) of the liver with the hepatocellular-specific contrast agent gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) in comparison to precontrast MRI and spiral computed tomography (CT) in the specific diagnosis of(More)
OBJECTIVES To evaluate the performance of black-blood diffusion-weighted (DW)-EPI sequences with parallel imaging for the detection of focal liver lesions in comparison with a standard T2-weighted (T2-w) sequence. MATERIALS AND METHODS Twenty patients with known or suspected focal liver lesions underwent liver MRI using a DW-EPI sequence with a b-value of(More)
Axonal and dendritic integrity is affected early in Alzheimer's disease (AD). Studies using region of interest or voxel-based analysis of diffusion tensor imaging data found significant decline of fractional anisotropy, a marker of fiber tract integrity, in selected white matter areas. We applied a multivariate network analysis based on principal component(More)
To compare 3D non-enhanced ECG-gated inflow-dependent MRA (NE-MRA) vs. continuous table movement (CTM) MR-angiography and time-resolved TWIST-MRA in the calf station at 3.0 T in a clinical patient collective. 36 patients (27 male/9 female, 66.1 ± 14.4 years) with PAOD (stage II–IV) underwent during a single MRI: NE-MRA, contrast-enhanced CTM-MRA and(More)
The diagnostic accuracy of screening for bone metastases was evaluated using whole-body magnetic resonance imaging (WB-MRI) compared with combined fluorodeoxyglucose (FDG) positron emission tomography (PET) and computed tomography (CT) (FDG-PET-CT). In a prospective, blinded study, 30 consecutive patients (18 female, 12 male; 24–76 years) with different(More)
OBJECTIVES Recent animal studies with dynamic contrast enhanced magnetic resonance imaging have demonstrated that a separable compartment model provides more accurate assessments of glomerular filtration than the Patlak model. In this study, the feasibility of the separable compartment model for the measurement of perfusion and filtration in healthy humans(More)
OBJECTIVE The objective of this study was to compare the accuracy in staging of various malignant tumors with whole-body magnetic resonance imaging (WB-MRI) using parallel imaging (PAT) and positron emission tomography-computed tomography (PET-CT). MATERIALS AND METHODS In a prospective study, 41 patients withoncologic diseases underwent(More)
PURPOSE To differentiate healthy kidneys from diseased kidneys, we propose a combined magnetic resonance (MR) examination that includes measurements of renal arterial blood flow and parenchymal perfusion. MATERIALS AND METHODS A total of 130 kidneys (patients/healthy volunteers: 83/47) were examined using renal artery MR flow measurements and renal(More)
PURPOSE To retrospectively compare three-dimensional gadolinium-enhanced magnetic resonance (MR) angiography, performed with an integrated parallel acquisition technique for high isotropic spatial resolution, with selective digital subtraction angiography (DSA) and intravascular ultrasonography (US) for accuracy of diameter and area measurements in renal(More)