Stefan Kastenholz

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Traceability of artefacts induces the means of understanding the complexity of logical relations existing among artefacts, that are created during software development. In turn, this provides the necessary knowledge for reasoning about the quality of software. With the inception of Model-Driven Software Engineering, the advantage of generating traceability(More)
With the advent of Model-driven Software Engineering, the advantage of generating trace links between source and target model elements automatically, eases the problem of creating and maintaining traceability data. Yet, an existing transformation engine as in the above case is not always given in model-based development, (i.e. when transformations are(More)
This phase II trial assessed temsirolimus, an inhibitor of mammalian target of rapamycin (mTOR), as second-line therapy in patients with metastatic transitional carcinoma of the urothelium (TCCU) after failure of platinum containing therapy. From June/2009 to June/2011, we enrolled 15 patients in this trial. Primary endpoint was overall survival, as(More)
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