Stefan Iosif Drăgulescu

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AIMS This report describes the baseline characteristics of patients in the Reduction of Events with Darbepoetin alfa in Heart Failure trial (RED-HF) which is testing the hypothesis that anaemia correction with darbepoetin alfa will reduce the composite endpoint of death from any cause or hospital admission for worsening heart failure, and improve other(More)
The effects on sexual behaviour of acute low doses of methylendioxymethamphetamine (MDMA) (0.3, 1, 3 mg/kg/i.p.), alone or in combination with exposure to loud music (1 h stimulation), were investigated in Wistar rats. Results indicate that acute MDMA, at dose of 3 mg/kg, notably impaired copulatory behavior of sexually experienced male rats. In particular,(More)
Ecocardiografic nu rareori sunt prezente modific\ri la nivelul atriului drept, date de persisten]a unor structuri embriologice care nu s-au resorbit. Diagnosticul [i conduita terapeutic\ ulterioar\ pentru ace[ti pacien]i este greu de stabilit. O astfel de structur\ este valva lui Eustachio, descris\ frecvent [i care uneori se înso]e[te de complica]ii(More)
Secondary or pathologic fractures, associated with osteosarcoma, have been considered for a long time to be a negative prognosis regarding its evolution in the patients. The aim of this study was to evaluate the prognostic importance of such pathologic fractures in osteosarcoma patients receiving new therapies as well as the best conditions for surgery(More)
REZUMAT MULTIPLE ELECTRODES AGGREGOMETRY A NEW METHOD TO ASSESS THE PLATELET REACTIVITY IN NON-ST ELEVATION ACUTE CORONARY SYNDROME PATIENTS Daniela Maximov1, Adina Ionac2, Alina Lupu1, Cristian Mornos2, Stefan I. Dragulescu2 Introduction: Non-ST segment elevation acute coronary syndrome (NSTE ACS) patients are at high risk for development of new(More)
Atrial myxomas are the most common primary heart tumors and the early diagnosis is rather difficult, since the clinical aspects are often non-specific, varying widely. The association of coronary artery disease to myxoma has not been frequently reported and may sometimes determine an early diagnosis of the tumor, before serious complications as systemic(More)
Department of Cardiovascular Surgery, Institute for Cardiovascular Medicine Timisoara, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania Department of Intensive Care, Institute for Cardiovascular Medicine Timisoara, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania Department of Cardiology, Institute for Cardiovascular(More)
BACKGROUND Torsional and longitudinal deformations are essential components of left ventricular (LV) performance. A precise assessment of LV function must take into account both LV torsion (LVtor) and global longitudinal strain (LVE). We compared a new 2D-strain parameter, LVtor x LVE, with several other echocardiographic parameters, with respect to their(More)
The present study focuses on the application of a therapeutic strategy in patients with chronic severe lower limb ischaemia using a plasmid vector encoding the vascular endothelial growth factor (phVEGF165). It has been shown that VEGF promotes neo-vascularization and blood vessel network formation and thus might have the ability to improve blood-flow at(More)
BACKGROUND The clinical profile and outcome of nosocomial and non-nosocomial health care-associated native valve endocarditis are not well defined. OBJECTIVE To compare the characteristics and outcomes of community-associated and nosocomial and non-nosocomial health care-associated native valve endocarditis. DESIGN Prospective cohort study. SETTING 61(More)