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Stationary visual information has a stabilizing effect on posture, whereas moving visual information is destabilizing. We compared the influence of a stationary or moving fixation point to the influence of stationary or moving large-field stimulation, as well as the interaction between a fixation point and a large-field stimulus. We recorded body sway in 20(More)
We report seven unrelated families with mitochondrial tRNA(Ser(UCN)) gene mutations at three different loci. A novel G7497A mutation is found in two families, both of which present with progressive myopathy, ragged-red fibers, lactic acidosis, and deficiency of respiratory chain complexes I and IV. This mutation presumably affects the tertiary(More)
Dynamic Programming (DP) is a popular and efficient method for calculating disparity maps from stereo images. It allows for meeting real-time constraints even on low-cost hardware. Therefore, it is frequently used in real-world applications, although more accurate algorithms exist. We present a refined DP stereo processing algorithm which is based on a(More)
Alexander's law (AL) states that the slow-phase velocity of spontaneous nystagmus of peripheral vestibular origin is dependent on horizontal gaze position, with greater velocity when gaze is directed in the fast-phase direction. AL is thought to be a compensatory reaction resulting from adaptive changes in the horizontal ocular motor neural integrator.(More)
Visual input is highly relevant for safely stepping over obstacles. In this study, gaze-behaviour was investigated in elderly, middle-aged and young subjects as they walked on a treadmill repeatedly stepping over obstacles, which approached either on the right or left side. In between obstacle-steps, subjects visually fixated a target N or F located two or(More)
OBJECTIVE To evaluate a novel test for dynamic visual acuity (DVA) that uses an adaptive algorithm for changing the size of Landolt rings presented during active or passive head impulses, and to compare the results with search-coil head impulse testing. DESIGN Prospective study in healthy individuals and patients with peripheral vestibular deficits. (More)
INTRODUCTION Unrealistic optimism refers to the pervasive tendency of healthy individuals to underestimate their likelihood of future misfortune, including illness. The phenomenon shares a qualitative resemblance with anosognosia, a neurological disorder characterized by a deficient appreciation of manifest current illness or impairment. Unrealistic(More)
We present the unique case of a patient with a circumscribed solitary cerebral metastasis of a malignant melanoma extending from the medial part of the superior temporal gyrus to the lower part of the 1st long insular gyrus causing gait and stance instability and an ipsiversive tilt of the subjective visual vertical. Oculomotor disorders could not be(More)
The nystagmus in patients with vestibular disorders often has an eye position dependency, called Alexander's law, where the slow phase velocity is higher with gaze in the fast phase direction compared with gaze in the slow phase direction. Alexander's law has been hypothesized to arise either due to adaptive changes in the velocity-to-position neural(More)
Spontaneous nystagmus (SN) is a symptom of acute vestibular tone asymmetry. Alexander's Law (AL) states that slow-phase velocity of SN is higher when looking in the direction of fast-phases of nystagmus and lower in the slow-phase direction. Earlier explanations for AL predict that during SN, slow-phase eye velocity is a linear function of eye position,(More)