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In the past, the genetically diabetic-obese diabetes/diabetes (db/db) and obese/obese (ob/ob) mouse strains were used to investigate mechanisms of diabetes-impaired wound healing. Here we determined patterns of skin repair in genetically normal C57Bl/6J mice that were fed using a high fat diet (HFD) to induce a diabetes-obesity syndrome. Wound closure was(More)
BACKGROUND Expression and enzymatic activity of heme oxygenase (HO) has been implicated in the development, as well as in the resolution, of inflammatory conditions. Because inflammation is central to tissue repair, we investigated the presence and potential functions of HO in an excisional model of normal and diabetes-impaired wound repair in mice. (More)
To define the mechanism of nitric oxide (NO) action in the glomerulus, we attempted to identify genes that are regulated by NO in rat glomerular mesangial cells. We identified a Cu/Zn superoxide dismutase (SOD) that was strongly induced in these cells by treatment with S-nitroso-glutathione as a NO-donating agent. Bacterial lipopolysaccharide (LPS) acutely(More)
This study investigated the relation between word surprisal and pupil dilation during reading. Participants' eye movements and pupil size were recorded while they read single sentences. Surprisal values for each word in the sentence stimuli were estimated by both a recurrent neural network and a phrase-structure grammar. Higher surprisal corresponded to(More)
| Weighted Finite Automata (WFA) exploit self-similarities within single pictures and also sequences of pictures to remove spatial and temporal redundancies. Their implementation then combines techniques from hierarchical methods related to quadtrees and from vector-quantization to achieve performance results for low bit-rates which can be put on a par with(More)