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Consequences of resistance evolution in a Cas9-based sex conversion-suppression gene drive for insect pest management
TLDR
This study shows that in-frame drive-resistant alleles can be produced readily and inherently in a suppression gene-drive system, and confirms previous studies that simple homing CRISPR/Cas9 gene- drive designs will be ineffective. Expand
Morphological and Transcriptomic Analysis of a Beetle Chemosensory System Reveals a Gnathal Olfactory Center
TLDR
The analysis of the T. castaneum chemosensory system confirms that olfactory and gustatory perception are not organotopically separated to the antennae and mouthparts, respectively, and indicates that Holometabola have evolved a wider variety of solutions to chemoreception than previously assumed. Expand
Tissue-specific transcriptomics, chromosomal localization, and phylogeny of chemosensory and odorant binding proteins from the red flour beetle Tribolium castaneum reveal subgroup specificities for
TLDR
Most of the classic OBPs and all ABPIIs are likely involved in chemoreception, but the majority of the CSPs as well as the C-OBPs are not enriched in antennae or mouthparts, suggesting a more general role in the transport of hydrophobic molecules. Expand
3D Standard Brain of the Red Flour Beetle Tribolium Castaneum: A Tool to Study Metamorphic Development and Adult Plasticity
TLDR
Comparison of the averaged neuropil volumes revealed no sexual dimorphism in any of the reconstructed neuropils in A0 Tribolium brains, which will serve as future volumetric references after genetical manipulation especially regarding metamorphic development and adult plasticity. Expand
Enhanced genome assembly and a new official gene set for Tribolium castaneum
TLDR
An improved genome assembly and an enhanced genome annotation resulting in a new official gene set (OGS3) for Tribolium castaneum are presented, which significantly increase the quality of the genomic resources. Expand
The olfaction of a fire beetle leads to new concepts for early fire warning systems
Abstract The European fire beetle Melanophila cuspidata oviposits on stems damaged by fire to provide its xylophagous larvae with nutrition. We investigated the beetle's ability to estimate theExpand
Volatile Combustion Products of Wood Attract Acanthocnemus nigricans (Coleoptera: Acanthocnemidae)
TLDR
Abundances of beetles caught in traps baited with a mixture of the most attractive volatiles showed only a trend to higher numbers, and these results are discussed with respect to weather conditions and complementing infrared perception of the pyrophilic beetles. Expand
Hyperactive piggyBac transposase improves transformation efficiency in diverse insect species.
TLDR
It is demonstrated that the usage of helper plasmids encoding the hyPBase - irrespective of the codon-usage - also strikingly increases the rate of successful germline transformation in the Mediterranean fruit fly Ceratitis capitata, the red flour beetle Tribolium castaneum, and the vinegar fly Drosophila melanogaster. Expand
Perspective on the combined use of an independent transgenic sexing and a multifactorial reproductive sterility system to avoid resistance development against transgenic Sterile Insect Technique
TLDR
A combination of a completely independent transgenic sexing and a redundant reproductive male sterility system would meet the 'redundant killing' criteria for suppression of resistance development and could therefore be employed in large scale long-term suppression programs using biotechnologically enhanced SIT. Expand
Adult neurogenesis in the mushroom bodies of red flour beetles (Tribolium castaneum, Herbst) is influenced by the olfactory environment
TLDR
The results suggest that the generation of Kenyon cells during the first three days after adult eclosion is mainly genetically predetermined and a continuation of the developmental processes (nature), whereas from day four on proliferation seems to be mainly dependent on the odour environment (nurture). Expand
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