Stefan Borowski

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Next generation sequencing (NGS) has been a great success and is now a standard method of research in the life sciences. With this technology, dozens of whole genomes or hundreds of exomes can be sequenced in rather short time, producing huge amounts of data. Complex bioinformatics analyses are required to turn these data into scientific findings. In order(More)
Many applications based on finite element and finite difference methods include the solution of large sparse linear systems using preconditioned iterative methods. Matrix vector multiplication is one of the key operations that has a significant impact on the performance of any iterative solver. In this paper, recent developments in sparse storage formats on(More)
This paper provides a comprehensive performance evaluation of the NEC SX-8 system at the High Performance Computing Center Stuttgart which has been in operation since July 2005. It provides a description of the installed hardware together with its performance for some synthetic benchmarks and five real world applications. All the applications achieved(More)
Typing of X chromosomal short tandem repeat (X STR) markers has become a standard element of human forensic genetic analysis. Joint consideration of many X STR markers at a time increases their discriminatory power but, owing to physical linkage, requires inter-marker recombination rates to be accurately known. We estimated the recombination rates between(More)
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