Stefan Bösner

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A proper representation of the uncertainty involved in a prediction is an important prerequisite for the acceptance of machine learning and decision support technology in safety-critical application domains such as medical diagnosis. Despite the existence of various probabilistic approaches in these fields, there is arguably no method that is able to(More)
BACKGROUND/OBJECTIVE Chest pain is a common complaint and reason for consultation. We aimed to study the epidemiology of chest pain with respect to underlying aetiologies and to establish pre-work-up probabilities for the primary care setting. METHODS We included 1212 consecutive patients with chest pain, aged 35 years and older, attending 74 general(More)
BACKGROUND Chest wall syndrome (CWS) is the most frequent aetiology of chest pain in a primary care setting. OBJECTIVE The aims of the study are to describe the epidemiology, clinical characteristics and prognosis of CWS and to provide a simple decision rule for diagnosis. METHODS We included 1212 consecutive patients with chest pain aged 35 years and(More)
BACKGROUND Differential diagnosis is a crucial skill for primary care physicians. General practice plays an increasing important role in undergraduate medical education. Via general practice, students may be presented with an overview of the whole spectrum of differential diagnosis in regard to common symptoms encountered in primary care. This project(More)
AIM To investigate the frequencies of different and relevant underlying etiologies of chest pain in general practice. METHODS We systematically searched PubMed and EMBASE. Two reviewers independently rated the eligibility of publications and assessed the risk of bias of included studies. We extracted data to calculate the relative frequencies of different(More)
BACKGROUND Diagnostic reasoning in primary care patients with abdominal pain is a complex challenge for GPs. To ensure evidence-based decision making for this symptom, GPs need setting-specific knowledge about the prevalence, potential risks for diseases and chance of recovery or risk of undesirable courses of disease. AIM We conducted a systematic review(More)
BACKGROUND Chest pain raises concern for the possibility of coronary heart disease. Scoring methods have been developed to identify coronary heart disease in emergency settings, but not in primary care. METHODS Data were collected from a multicenter Swiss clinical cohort study including 672 consecutive patients with chest pain, who had visited one of 59(More)
BACKGROUND Headache is one of the most common symptoms in primary care. Most headaches are due to primary headaches and many headache sufferers do not receive a specific diagnosis. There is still a gap in research on how GPs diagnose and treat patients with headache. AIM To identify GPs' diagnostic approaches in patients presenting with headache. DESIGN(More)
BACKGROUND Diagnosing the aetiology of chest pain is challenging. There is still a lack of data on the diagnostic accuracy of signs and symptoms for acute coronary events in low-prevalence settings. AIM To evaluate the diagnostic accuracy of symptoms and signs in patients presenting to general practice with chest pain. DESIGN OF STUDY Cross-sectional(More)
BACKGROUND Chest pain is a common complaint and reason for consultation in primary care. Research related to gender differences in regard to Coronary Heart Disease (CHD) has been mainly conducted in hospital but not in primary care settings. We aimed to analyse gender differences in aetiology and clinical characteristics of chest pain and to provide gender(More)