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OBJECTIVE To determine candidate lesion-based criteria for a positive sacroiliac joint (SIJ) MRI based on bone marrow oedema (BMO) and/or erosion in non-radiographic axial spondyloarthritis (nr-axSpA); to compare the performance of lesion-based criteria with global evaluation by expert readers. METHODS Two independent cohorts A/B of 69/88 consecutive(More)
OBJECTIVE To validate a magnetic resonance imaging (MRI) reference criterion for a positive sacroiliac (SI) joint MRI finding based on the level of confidence in the classification of spondyloarthritis (SpA) by expert MRI readers. METHODS Four readers assessed SI joint MRIs in 2 inception cohorts (cohorts A and B) of 157 consecutive patients with back(More)
PURPOSE To evaluate the effect of removal and/or exchange of intrastromal corneal ring segments (ICRS, Intacs); specifically the risk factors, degree of reversibility, and visual outcomes. SETTING Gimbel Eye Centres, Calgary, Edmonton, and Vancouver, Canada. METHODS Prospective cohort data were collected on 71 eyes that had ICRS placement by 3 surgeons(More)
OBJECTIVE To assess the incremental diagnostic value of spine MRI evaluated separately from and combined with sacroiliac joint (SIJ) MRI in non-radiographic axial spondyloarthritis (nr-axSpA) compared with SIJ MRI alone. METHODS The study sample comprised two independent cohorts A/B of 130 consecutive patients aged ≤50 years with back pain, newly referred(More)
OBJECTIVE A recent consensus statement has suggested ≥3 corner inflammatory lesions (CILs) or several corner fatty lesions (CFLs) as candidate criteria indicative of axial spondyloarthritis (SpA) on magnetic resonance imaging (MRI) of the spine. The aim of this study was to evaluate the diagnostic utility of these cutoffs in nonradiographic axial SpA and(More)
OBJECTIVE To explore whether morphological features of fat infiltration (FI) on sacroiliac joint (SIJ) magnetic resonance imaging (MRI) contribute to diagnostic utility in 2 inception cohorts of patients with nonradiographic axial spondyloarthritis (nr-axSpA). METHODS Four blinded readers assessed SIJ MRI in 2 cohorts (A/B) of 157 consecutive patients(More)
INTRODUCTION Inflammation of the sacroiliac joints (SIJ) is a fundamental clinical feature of axial spondyloarthritis (SpA). The anatomy of the irregularly shaped SIJ is complex with an antero-inferior cartilaginous compartment containing central hyaline and peripheral fibrocartilage, and a dorso-superior ligamentous compartment. Several scoring modules to(More)
BACKGROUND We investigated the characteristics and causes of various uveitis subtypes in patients presenting to the Regional Eye Centre at the Royal Alexandra Hospital, University of Alberta, Edmonton, Alta., and estimated the incidence of anterior uveitis in northern Alberta. METHODS A retrospective study was conducted of all patients presenting with(More)
PURPOSE To report the unusual presentation of a confirmed iris lymphoma in the setting of posttransplant lymphoproliferative disorder. DESIGN Case report with clinicopathologic findings. METHODS The medical record was reviewed for clinical manifestations, course of disease, and pathologic and radiologic findings. RESULTS A 4-year-old girl who had(More)
OBJECTIVE To describe the characteristics of uveitis in a Canadian referral centre and to identify predictors of uveitis recurrence. DESIGN Retrospective cohort study. PARTICIPANTS Two hundred eighty-five patients with anterior uveitis, intermediate uveitis, or panuveitis. METHODS We conducted a retrospective study of all patients presenting with(More)
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