Stanley E Wolf

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Interleukin (IL) 12 is a proinflammatory cytokine produced by phagocytic cells, B cells, and other antigen-presenting ceils that modulates adaptive immune responses by favoring the generation o f T helper type 1 cells. IL-12 mediates some of its physiological activities by acting as a potent inducer of interferon (IFN) y production by T and natural killer(More)
The liver plays a crucial role in the acute phase response after injury; mechanisms responsible for transducing inflammatory signals to the nucleus to initiate this response are not known. The purpose of this study was to examine the induction of the novel Stat (signal transducer and activator of transcription) pathway in the liver after burn injury. Rats(More)
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