Stanisław Jankowski

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TenE. coli K1 strains isolated from the urine of children with urinary tract infections were sensitive to the bactericidal action of normal human serum (NHS). The role of the particular mechanisms of complement activation was determined in the process of killing these strains, showing variable sensitivity to the bactericidal action of NHS; three mechanisms(More)
The susceptibility od Proteus, Providencia, and Morganella strains to bactericidal action of human serum was examined. The percentage of survival was determined after one and three hours incubation with 50% human serum. The susceptible strains were treated by serum preparations with blocked classical or alternative complement activation pathways as well as(More)
Utilization of the complement system offers potential for the elimination of tumor cells by monoclonal antibodies (mAb) immunotherapy. Activation of the complement system causes tumor cell destruction by inducing complement lysis and promoting cell-mediated killing. In addition, complement can induce a strong inflammatory response, which might enhance other(More)
Demodex mites are common parasites in the hair follicles and in the pilosebaceous glands. Demodex folliculorum and D. brevis have been identified in humans and play a role in three facial conditions: Pityriasis folliculorum, rosacea-like demodicidosis and Demodicidosis gravis. The highly infected sites by this mites are: forehead, area around the orbit,(More)
The influence of subinhibitory concentrations (1/2, 1/4, 1/8, 1/16 and 1/32 MIC) of amikacin and ciprofloxacin on the morphology and adherence of uropathogenic strains was studied. Intensity of morphological changes was proportional to the concentrations of these antibiotics. Morphological changes were the most prominent after bacterial exposure to sub-MICs(More)
The bactericidal action of serum is one of the mechanisms protecting higher organisms from infection by gram-negative bacteria. Complement (C) activation by the classical or alternative pathways plays a main role in this protective action. The bactericidal activity of normal newborn sera against some gram-negative bacteria is less efficient than that of(More)
BACKGROUND The susceptibility of bacteria to the bactericidal activity of serum depends on the structure and organization of the bacterial outer membrane. It is known that the structure of the O-specific polysaccharide chain of lipopolysaccharide (LPS) plays an important role in the resistance of bacteria to host immune defenses. OBJECTIVES The(More)
The susceptibility ofEscherichia coli strains with K1 surface antigen (K1+) and rods without this antigen (K1−) to the bactericidal action of normal bovine serum and human normal cord serum was determined. SeventyE. coli strains (35 K1+ and 35 K1−) were isolated from urine obtained from children with urinary tract infections. The strains investigated showed(More)
The purpose of this study was to answer the question whether the exposure of bacterial cells to ozone results in changes of their sensitivity to the bactericidal action of normal bovine serum (NBS). Our initial studies have demonstrated that contact of bacteria with O3 enhances serum-mediated killing.
The role of ozone in the susceptibility of clinical isolates of Acinetobacter anitratus and Pseudomonas aeruginosa to serum was investigated. It was found that ozone-treated cells were more susceptible to complement-mediated killing serum. These results suggest that ozone damage or change of cell membrane leads to a more rapid penetration of the membrane(More)